Gene description for P4HB
Gene name prolyl 4-hydroxylase subunit beta
Gene symbol P4HB
Other names/aliases CLCRP1
DSI
ERBA2L
GIT
P4Hbeta
PDI
PDIA1
PHDB
PO4DB
PO4HB
PROHB
Species Homo sapiens
 Experiment description of studies that identified P4HB in Esophageal cancer cells

1
Experiment ID2893
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameYES2
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID2894
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE30
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID2895
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE150
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID2897
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE70
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID2898
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE140
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID2899
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameCOLO680N
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID2904
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE150
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID2905
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameKYSE150
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID2906
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameYES2
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID2907
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33732415   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway
AuthorsGao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q.
Journal name J Extracell Vesicles
Publication year2021
SampleEsophageal cancer cells
Sample nameYES2
Isolation/purification methodsFiltration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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